Bol died at the University of Virginia Hospital in Charlottesville, where he was being treated for severe kidney trouble and a painful skin condition, Tom Prichard, executive director of the group Sudan Sunrise, said in an e-mail.
Bol played three seasons with the Golden State Warriors during his NBA career. His blocking skills and ease at shooting three-pointers made him a fan favorite.
Warriors coach Don Nelson told the Chronicle’s Rusty Simmons that Manute, "was a wonderful man with a terrific sense of humor. He had everybody on our team in stitches all the time."
Bol also played for Washington, Philadelphia and Miami, averaging 2.6 points, 4.2 rebounds and 3.3 blocks for his career. He led the league in blocks in 1985-86 with Washington (5.0 per game) and in 1988-89 with Golden State (4.3 a game).
After the NBA, Bol worked closely as an advisory board member of Sudan Sunrise, a humanitarian group which promotes reconciliation in Sudan.
"Sudan and the world have lost a hero and an example for all of us," Sudan Sunrise Executive Director Tom Prichard said. "Manute, we'll miss you. Our prayers and best wishes go out to all his family, and all who mourn his loss."
"Despite his accomplishments on the court, his lasting legacy will be the tireless work and causes he promoted in his native Sudan and the cities in which he played," the club said in a statement.
Bol was hospitalized in mid-May during a stopover in Washington after returning to the United States from Sudan. Prichard said then that Bol was in Sudan to help build a school in conjunction with Sudan Sunrise but stayed longer than anticipated after the president of southern Sudan asked him to make election appearances and use his influence to counter corruption in the county.
Bol had undergone three dialysis treatments and developed Stevens-Johnson Syndrome, a condition that caused him to lose patches of skin. Prichard said the skin around Bol's mouth was so sore he went 11 days without eating and could barely talk.
Prichard said it's believed Bol contracted the skin disease as a reaction to kidney medication he took while in Africa.
Janis Ricker, operations manager of Sudan Sunrise, said Saturday the organization will continue its work building the school in Bol's home village in southern Sudan. She said Bol's goal was to build 41 schools throughout Sudan.