It was a heartbreaking loss, and reactions came fast and furious across the Twittersphere as the San Francisco 49ers failed to add a much-coveted sixth championship to the team's illustrious trophy case.
From the heartfelt to the comedic, here's just a sampling of what some people had to say on Twitter about the 49ers' loss.
[View the story "Twittersphere reacts to 49ers' Super Bowl loss" on Storify]
