Zika Vaccines Work in Monkeys, Boosting Hopes for People | NBC Bay Area
Zika Virus Outbreak

Zika Virus Outbreak

Coverage of the spread of the Zika virus in the Americas

Zika Vaccines Work in Monkeys, Boosting Hopes for People

The experiment involved a traditional vaccine and two more cutting-edge ones

    processing...

    NEWSLETTERS

    AP
    In this Feb. 11, 2016, file photo of aedes aegypti mosquitoes are seen in a mosquito cage at a laboratory in Cucuta, Colombia.

    Three experimental Zika vaccines protected monkeys against infection from the virus, an encouraging sign as research moves into studies in people.

    The success in monkeys, which involved a traditional vaccine and two more cutting-edge ones, "brings us one step closer to a safe and effective Zika vaccine," said Dr. Dan Barouch of Beth Israel Deaconess Medical Center in Boston. "But of course, there's a lot more work to do."

    UK Police: 'Fatalities' at Grande Concert

    [NATL] UK Police: 'Fatalities' at Grande Concert

    British police said an explosion at an Ariana Grande concert at Manchester Arena killed 22 people, including children, and injured more than 50. 

    (Published 4 hours ago)

    Barouch and others reported the results in a paper released Thursday by the journal Science. One of the vaccines is expected to enter preliminary human studies this year.

    At least two other vaccines have reached that point already. Inovio Pharmaceuticals announced last week that it had injected its first participant. The National Institute of Allergy and Infectious Diseases gave its first vaccine Tuesday. Both studies focus on assessing vaccine safety.

    WATCH: Pippa Middleton Post-Wedding Kiss

    [NATL] WATCH: Pippa Middleton Post-Wedding Kiss

    Pippa Middleton and James Matthews kiss after their wedding at St Mark's Church in Englefield, England, on Saturday, May 20, 2017. Middleton, the sister of Kate, Duchess of Cambridge, married hedge fund manager James Matthews in a ceremony Saturday. Her niece and nephew, Prince George and Princess Charlotte, were in the wedding party, along with sister Kate and princes Harry and William.

    (Published Saturday, May 20, 2017)

    Efforts to develop a vaccine began after a massive Zika outbreak last year in Brazil, which showed that infection of pregnant women can harm fetal brain development.

    In the monkey study, one vaccine followed the traditional approach, using a dead Zika virus to train the body for fighting off infection. It was injected into eight rhesus monkeys and followed by a booster shot a month later. A month after the booster, the monkeys got a dose of Zika virus.

    The 'Greatest Show on Earth' Says Goodbye

    [NATL-NY] The 'Greatest Show on Earth' Says Goodbye

    The Ringling Brothers and Barnum & Bailey Circus that has wowed crowds for 146 years with its "Greatest Show on Earth" is taking its final bow on Sunday.

    (Published Sunday, May 21, 2017)

    None showed any sign of the virus in their blood for the week they were followed. In contrast, eight other monkeys that had gotten a sham vaccine became infected.

    That vaccine, developed at the Walter Reade Army Institute of Research in Silver Spring, Maryland, is expected to begin human testing in October.

    The other two vaccines, produced at Beth Israel and not yet scheduled for human studies, delivered only the DNA of a single virus gene. That spurred the monkeys' bodies to pump out a protein found in the Zika virus, which in turn gave their immune systems to attack on the full virus.

    The two vaccines completely protected a total of eight monkeys against infection.

    ‘T-Rex’ Spooks Horses on City Street

    [NATL] ‘T-Rex’ Spooks Horses on City Street

    A person in a Tyrannosaurus Rex costume allegedly growled at a pair of horses pulling a carriage in Charleston, South Carolina. The horses were frightened and caused the carriage to jackknife, injuring the driver.

    (Published Friday, May 19, 2017)

    The results "add some encouragement that this might work in humans," said Dr. Anthony Fauci, director of the federal infectious disease institute, who was not involved in the study. The total protection is "good news," he said.

    Experts said it's impossible to know when a Zika vaccine will be approved for use.

    'Not Going to Stop': Haley Promises Support for Syrians

    [NATL] 'Not Going to Stop': Haley Promises Support for Syrians

    Nikki Haley, U.S. ambassador to the United Nations, spent two days in Jordan and toured the Zaatari camp for Syrian refugees on Sunday. She said that the Trump administration's stated intent to slash humanitarian aid worldwide would not affect U.S. support for the crisis in Syria.

    (Published Sunday, May 21, 2017)

    "It's not going to be this year, for sure," Barouch said.

    Fauci said it might be early 2018 if not later.

    Three Men Arrested in Death of 6-Year-Old

    [NATL] Three Men Arrested in Death of 6-Year-Old

    Three young men were arrested hours after a 6-year-old boy was found shot dead in his mother's stolen car near Jackson, Mississippi on Thursday, May 18, 2017. Authorities say the suspects will be charged with capital murder.

    (Published Friday, May 19, 2017)