The president's appearence comes less than two weeks after he had inserted two stents into his native coronary artery in New York. Mr. Clinton had the procedure to fix an obstructed bypass graft from five years ago.
Clinton is appearing in the Zellerbach Auditorium on campus at 3:30 p.m. Wednesday as a special guest of the university's Blum Center for Developing Economies.
Clinton last spoke at UC Berkeley in 2002, when talked about globalization and the gap between rich and poor.
Zellerbach Auditorium seats about 2,000 people and the majority of the seats will be reserved for students.
The title of Clinton's speech is "Global Citizenship: Turning Good Intention into Positive Action."
The Blum Center for Developing Economies was established in 2006 to tap the energy and talent of the nation's top public teaching and research university to help the nearly 3 billion people in the world who live on less than $2 a day.