The celebrities will be in town Thursday for ONEXONE Foundation, a charitable organization committed to fighting health issues and preserving the lives of children locally and globally, first charity fundraiser.
The group launched its U.S. operation earlier this year.
Damon will be the ambassador for the evening, which will feature an appearance by special guest Dr. Jeffrey Sachs, author of “The End of Poverty” and one of TIME magazine’s 100 Most Influential People.
Grammy Award-winnerâ Wyclef Jean will be the music ambassador.
The evening will include a special performance by Josh Groban along with musical performances by Wyclef Jean, The African Children’s Choir and other special guests
The evening will also honor music icon and legendary performer Carlos Santana with the ONEXONE Difference Award.
The event will take place this Thursday at the Concourse Exhibition Center in San Francisco.
David Arquette started his tour of San Francisco early on Thursday by serving food to people in need at the Arriba Juntos food pantry.