San Francisco nemesis Paul Goldschmidt hit a two-run homer to help Jeremy Hellickson get his first win with for Arizona in the Diamondbacks' 5-1 victory over the struggling Giants on Sunday.
Chris Owings added a two-run single and A.J. Pollock had three hits, scored two runs and made a run-saving diving catch for the Diamondbacks, who took three of four from the defending World Series champions.
Tim Hudson (0-2) allowed five runs and six hits in five innings as San Francisco lost for the ninth time in 10 games.
One day after snapping an eight-game losing streak, the Giants found themselves in an early hole against the Diamondbacks thanks to a player who has done plenty of damage against San Francisco in recent years.
Goldschmidt hit the first pitch he saw from Hudson over the left-field fence for a two-run shot. That was Goldschmidt's 10th homer in the past four seasons against San Francisco, tied with Wilin Rosario for the most against the team. Goldschmidt also has the most hits (56), RBIs (39) and runs (35) against the Giants in that span.
Hudson, who has gotten only one of support in three starts, lost his control in the third and the Giants never recovered. Hudson walked two batters and hit Jordan Pacheco with the bases loaded to force in a run before Owings broke the game open with his hit that made it 5-1.
That was more than enough for Hellickson (1-2), who allowed one runs and eight hits in 6 2-3 innings.
San Francisco got on the board in the first when Nori Aoki doubled and scored on Angel Pagan's sacrifice fly. But three double plays and Pollock's diving catch in center to rob Hudson and end the second inning with two runners on base helped Hellickson avoid any more damage.
Hellickson, acquired in an offseason trade from Tampa Bay, lost his first two starts against San Francisco and San Diego before getting the win to cap a successful road trip for Arizona.
The Diamondbacks won four of seven against San Diego and San Francisco for their first winning trip since sweeping Colorado in a three-game series last June.
Diamondbacks: C Gerard Laird (back) is eligible to come off the disabled list Friday.
Giants: Manager Bruce Bochy said he will likely use either Ryan Vogelsong or Yusmeiro Petit in place of injured starter Jake Peavy on Thursday against Los Angeles rather than moving up the rest of the rotation because of Monday's off-day.
Diamondbacks: Off on Monday before Texas native Chase Anderson (0-0) takes on the Rangers for the first time in his career to start a two-game series Tuesday.
Giants: San Francisco get its first off-day of the season Monday after playing 14 straight days. The Giants then open a three-game series at home on Tuesday against the Los Angeles Dodgers.