After two straight road wins in the Midwest, the Oakland A's returned to the coast and lost the opener in the a three-game set with the Los Angeles Angels, 8-3.
Shohei Ohtani and Kole Calhoun each hit two-run homers and Griffin Canning allowed only three hits over six innings for the Angels.
Both homers were to center field and came on sinker pitches by Tanner Anderson (0-3). Calhoun's drive gave Los Angeles a 2-1 lead in the second. Ohtani's shot came during a five-run third that broke the game open.
Canning (3-4) surrendered both his runs on solo shots. Ramon Laureano lined a slider over the wall in left-center in the second and Matt Olson connected on a fastball in the fourth.
The right-hander struck out six and worked at least six innings for the sixth time in 11 starts.
Luis Rengifo had three hits, including a two-run single in the third that chased Anderson, who had his shortest outing in four major-league starts. The right-hander went 2 2/3 innings and allowed seven runs and eight hits.
It is only the third time this year, and first since late April, that the Angels have won at least four straight games. Their longest winning streak is six, which occurred the second week of the season.