CHICAGO -- Kyle Hendricks limited San Francisco to one run and two hits over seven innings, Ben Zobrist lined a tiebreaking two-run double in the seventh and the Chicago Cubs beat the Giants 6-2 on Friday.
Hendricks (4-3) struck out seven and walked two to help the Cubs open the series on a winning note after a two-game sweep by Cleveland at Wrigley Field.
Gorkys Hernandez had two of San Francisco's four hits - a leadoff homer in the fourth and single in the sixth. Evan Longoria added an RBI single against Pedro Strop in the ninth, but the Giants fell to 0-3 on an eight-game trip. They have been outscored 21-5.
The Cubs scored four in the seventh while chasing Derek Holland to grab a 5-1 lead. Zobrist's double to left against Will Smith made it 3-1, and Kris Bryant added a two-run single off Cory Gearrin. Addison Russell made it 6-1 with an RBI single in the eighth, and the Cubs hung on for the victory.
Holland (2-6) gave up three runs (two earned) and five hits. He left with none out in the seventh after hitting Javier Baez and walking Ian Happ.
Giants: LHP Madison Bumgarner (fractured pinky on his throwing hand) is scheduled to throw approximately 45 pitches in a rehab start with Triple-A Sacramento Saturday. ... 2B Joe Panik (sprained left thumb) continues to make progress and could begin a rehab assignment before the team concludes its current road trip that runs through Wednesday.
Giants: RHP Chris Stratton (5-3, 4.92 ERA) tries to win his third straight start, though he's only gone five innings in each of his past two.
Cubs: LHP Jose Quintana (5-3, 4.47) looks to build on a dominant start after throwing one-hit ball over seven innings in a 10-0 win at Cincinnati on Saturday.