The annual New York film festival, co-created by Robert De Niro, announced the selection Monday.
The film is being advertised as the "final chapter" in the "Shrek" series. It's also the first "Shrek" released in 3-D.
The ninth annual Tribeca Film Festival runs through May 2. The rest of its slate will be announced in the coming weeks.
Related Content from AccessHollywood.com:
VIEW THE PHOTOS: MovieMantz: Best Movies of the Decade
PLAY IT NOW: Access Extended: 'Shrek The Musical' Premiere
PLAY IT NOW: Brian D'Arcy James Talks 'Shrek,' The Broadway Musical