On Sunday, Buster Posey and rookie Zach Green each had two hits.
A day later, the reward for a job well done is a night off.
With the Cubs starting right-handed pitcher Alec Mills in the opener of a three-game series at Oracle Park on Monday, Giants manager Bruce Bochy is going with left-handed hitting catcher Stephen Vogt behind the plate and switch-hitter Pablo Sandoval at third base.
Brandon Belt and and Joe Panik are back in the lineup getting the day off Sunday.
The Giants will hand the ball to rookie Shaun Anderson, who is 3-2 with a 4.87 ERA in 12 starts this season.
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Coverage begins at 5:30 p.m. with Giants Pregame Live on NBC Sports Bay Area and streaming on the My Teams app.
Here are teh full Cubs-Giants lineups:
Chicago Cubs (54-45)
1. Kyle Schwarber (L) LF
2. Javier Baez (R) SS
3. Kris Bryant (R) 3B
4. Anthony Rizzo (L) 1B
5. Robel Garcia (S) 2B
6. Jason Heyward (L) RF
7. Albert Almora Jr. (R) CF
8. Martin Maldonado (R) C
9. Alec Mills (R) P (0-0, 4.50 ERA)
San Francisco Giants (50-50)
1. Brandon Belt (L) 1B
2. Mike Yastrzemski (L) LF
3. Pablo Sandoval (S) 3B
4. Stephen Vogt (L) C
5. Brandon Crawford (L) SS
6. Kevin Pillar (R) CF
7. Austin Slater (R) RF
8. Joe Panik (L) 2B
9. Shaun Anderson (R) P (3-2, 4.87)