The Giants will be closing out their time in the Windy City on Thursday with a matinee game as they send former Cub Jeff Samardzija to the hill.
Samardzija enters with a 9-9 record and sports a 3.54 ERA. He most recently earned a no-decision after throwing 5 1/3 innings in the Giants' 10-9 win in Arizona on Friday night.
The Cubs will counter with Kyle Hendricks, who owns nearly identical numbers. The Chicago righty has an 8-9 record and a 3.37 ERA on the year.
Hendricks is making his regular-season debut against San Francisco, but he has faced off with the Orange and Black before. In the 2016 NLDS, Hendricks got the start in Game 2 and pitched 3 2/3 innings, allowing two runs as the Cubs won 5-2 inside the Friendly Confines.
Buster Posey is back behind the plate for the Giants after being off Wednesday and Scooter Gennett slides down to the seventh spot in the lineup after hitting second in last night's game.
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Here are how the lineups look to shape up as the Cubs play host to the Giants on Thursday. You can follow the action on NBC Sports Bay Area or by downloading and streaming on the MyTeams app.
San Francisco Giants (63-64)
Mike Yastrzemski, RF
Buster Posey, C
Alex Dickerson, LF
Evan Longoria, 3B
Brandon Belt, 1B
Kevin Pillar, CF
Scooter Gennett, 2B
Brandon Crawford, SS
Jeff Samardzija, P (9-9, 3.54 ERA)
Chicago Cubs (68-58)
Jason Heyward, CF
Nicholas Castellanos, RF
Kris Bryant, 3B
Anthony Rizzo, 1B
Javier Baez, SS
Kyle Schwarber, LF
Ian Happ, 2B
Victor Caratini, C
Kyle Hendricks, P (8-9, 3.27 ERA)