The crash happened shortly before 8 p.m. Wednesday at the intersection of Sunset Boulevard and Sunset Plaza Drive, LA County Sheriff's spokesman Sgt. Joseph Morien told The Associated Press.
The lefthander was taken to a Cedar-Sinai Medical Center for observation, but Morien said he doesn't have any details on his condition.
"It was just to be checked out if he had injuries or not, and I believe he was released from the hospital," the sergeant said.
City News Service said the other driver wasn't hurt.
The Giants open the season later Thursday against the Los Angeles Dodgers. Zito, 32, who won a Cy Young Award in 2002, but has struggled since signing a $16-million, seven-year deal with the Giants. He has posted a 40-57 record since joining the Giants and was not even placed on the post-season roster for the World Series champs last year. Still, Zito is the winner and the team's No. 5 starter, had been expected to pitch over the weekend.