OAKLAND -- George Springer went 6 for 6 with a home run to match a Houston record as the Astros routed the Oakland Athletics 16-2 on Monday night.
Last year's World Series MVP doubled and scored in the first inning, hit a three-run homer in the second and then singled and scored in the fourth. Needing a triple for the cycle, he reached on infield singles in the fifth and seventh before adding a fourth single up the middle in the ninth.
Springer's batting average jumped from .264 to .292. He became the second player in team history to go 6 for 6 and the first to do it in a nine-inning game. Hall of Famer Joe Morgan accomplished the feat in a 12-inning game against the Milwaukee Braves on July 8, 1965.
Houston set season highs for runs and hits (20) in its most lopsided win this season. The Astros beat the A's 11-0 on April 28.
Dallas Keuchel (2-5) yielded one run and five hits over eight innings. The Houston left-hander, who gave up three homers and six runs the last time he faced the A's on April 27, struck out four and walked two.
Jonathan Lucroy had two hits and an RBI for Oakland.
The A's played without outfielder Stephen Piscotty, whose mother died late Sunday night, less than a year after being diagnosed with Lou Gehrig's Disease.
Gretchen Piscotty was diagnosed with ALS in May 2017 when her son was with St. Louis. The Cardinals traded him to Oakland in December in part to allow Piscotty to be closer to his home in the East Bay suburb of Pleasanton during his mother's terminal illness.
Gonzalez hit a two-run homer in the fourth, when the Astros scored six runs.
Oakland lefty Brett Anderson (0-1) failed to make it out of the fourth in his first start at the Coliseum in an A's uniform since Sept. 22, 2013. Anderson allowed seven earned runs and 10 hits.
Athletics: LHP Ryan Buchter (strained left shoulder) continues to do strength and conditioning work but has not resumed throwing.
LHP Sean Manaea (4-3, 1.63 ERA) makes his first start in Oakland since pitching the majors' first no-hitter this season on April 21. Manaea has a 12-inning hitless streak at the Coliseum. RHP Lance McCullers Jr. (4-1, 3.73) gets the ball for Houston. The 2017 All-Star has gone at least six innings in each of his four starts this season.