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The Giants, who had won six straight home series, couldn't pull it off this weekend losing to the Cincinnati Red 5-2 on Sunday.
Aaron Harang ended the worst winless stretch of his career with his first victory since late May, Brandon Phillips and Adam Rosales each homered in Cincinnati's win.
The lowly Reds -- led by former San Francisco skipper Dusty Baker -- had to feel pretty good about themselves after taking this series, in which they won both games started by Giants All-Stars Matt Cain and Tim Lincecum.
Starting Monday, division rivals Los Angeles Dodgers come to town for a three-game series.
Tickets are still available for Monday and Tuesday night, but Wednesday's day game is nearly sold out.
Reds third baseman Scott Rolen was evaluated in Cincinnati on Sunday for concussion-like symptoms and will remain inactive for several more days.
Rolen was scratched from Saturday's starting lineup against the San Francisco Giants and then sent home to be examined by concussion specialist Dr. John Brannan.
Rolen was hit in the head by a pitch by former teammate Jason Marquis in the seventh inning of last Sunday's game against the Colorado Rockies.